Prevention Research Center In the Department of Medicine

Project Detail

Title: Innovative Obesity Prevention for African-American Girls
Researchers: Thomas Robinson, MD, MPH - Principal Investigator
William Haskell, PhD
Joel Killen, PhD
Helena Kraemer, PhD
Donna Matheson, PhD
Leslie Pruitt, PhD
C. Barr Taylor, MD, Dept. of Psychiatry and Behavioral Sciences; Darrell M. Wilson, Dept. of Pediatrics;
Funding Agency: National Institutes of Health
Duration: 8/1/1999 to 5/31/2002

Project Description:

This study proposes to test the efficacy of a dance program and a family-based intervention to reduce television, videotape and video game use to reduce weight gain among African-American pre-adolescent girls from lower socioeconomic status families. In a twelve-week controlled, school-based pilot study of using dance during physical education classes, we demonstrated that

1. dance is a feasible and acceptable form of physical activity for low-income African-American girls and

2. a dance intervention can result in significant reductions in body mass index (BMI) and improved physical fitness among girls.

In two pilot studies of reducing television viewing in 8-10 year olds, we demonstrated that

1. it is possible to significantly reduce children's television, videotape and video game use and

2. that an intervention reducing children's television, videotape and video game use can result in clinically significant decreases in BMI, triceps skinfold thickness and waist-to-hip ratio.

Interventions and measures will be developed during a 20-month formative evaluation period, using interviews and focus groups. Sixty 8-10 year old, low SES African-American girls and their families will participate in a twelve-week pilot test of intervention methods and measurement protocols. These results will lead to a renewal application for a 2-year randomized, controlled trial involving 240 African-American 8-10 year old girls and their families. Half will be randomized to the dance and television reduction intervention and half will be randomized to a non-specific "active placebo" control group.

In-home surveys of activity, inactivity and dietary behaviors and measures of height, weight, triceps skinfold thickness, waist & hip circumferences, Tanner stage of sexual maturation and blood pressure will occur at baseline and every six months. Four days of activity and heart rate monitoring, three 24-hour dietary recalls and fasting blood lipids and measures of insulin resistance will occur annually. DNA will be collected at baseline to examine the role of genetic polymorphisms on response to the intervention. We will use random regression models to test the following hypothesis Compared to controls, girls in the treatment group will significantly reduce their weight gain over the two-year study period.

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